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Search Results for " monomethyl auristatin e "

20

Compounds

Cat No. Product Name Synonyms Targets
T6897 Monomethyl auristatin E Vedotin,MMAE Apoptosis , Microtubule Associated
Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity.
T10948 MMAE-d8 D8-MMAE,D8-Monomethyl auristatin E Others
D8-MMAE (D8-Monomethyl auristatin E) is an effective mitotic inhibitor and tubulin inhibitor, deuterated MMAE.
T18312 Mc-MMAE Maleimidocaproyl-monomethylauristatin E Microtubule Associated
Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor.
T18473 N3-PEG3-vc-PAB-MMAE Others
N3-PEG3-vc-PAB-MMAE, a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC), features the integration of monomethyl auristatin E (MMAE), a tubulin inhibitor, via a 3-unit polyethylene glycol (PEG) linker. Th...
T79039 GGGDTDTC-Mc-vc-PAB-MMAE
GGGDTDTC-Mc-vc-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugates (ADCs), incorporating the tubulin inhibitor monomethyl auristatin E (MMAE) as the cytotoxic component [1].
T70958 Dov-Val-Dil-OH TFA
Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the po...
T40568 Fmoc-MMAE
Fmoc-MMAE, a protective group-conjugated variant of monomethyl auristatin E (MMAE), serves as a powerful inhibitor of tubulin. It finds application in the synthesis of antibody-drug conjugates (ADC).
T18736 SuO-Val-Cit-PAB-MMAE Others
SuO-Val-Cit-PAB-MMAE is an ADC (antibody-drug conjugate) linker comprising the anti-mitotic monomethyl auristatin E (MMAE, a tubulin inhibitor) connected through the SuO-Val-Cit-PAB peptide.
T18679 SC-VC-PAB-MMAE Others
SC-VC-PAB-MMAE is a potent antitumor drug-linker conjugate for antibody-drug conjugates (ADCs), comprising the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor) connected through the cleavable linker...
T17817 DBCO-(PEG)3-VC-PAB-MMAE Others
DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor acting as a toxin payload in antibody-drug conjugates, is conjugated to a DBCO-(PEG)3-vc-PAB linker.
T82380 Fmoc-VAP-MMAE
Fmoc-VAP-MMAE is a conjugate utilized in antibody-drug conjugates (ADCs), comprising a tubulin inhibitor, monomethyl auristatin E (MMAE), connected via an ADC linker, and shielded by a fluorenylmethyloxycarbonyl (Fmoc) p...
T18303 Mal-Phe-C4-VC-PAB-MMAE Others
Mal-Phe-C4-VC-PAB-MMAE is a chemical compound resulting from the conjugation of monomethyl auristatin E (MMAE), a potent tubulin inhibitor serving as a toxin payload in antibody-drug conjugates, with a Mal-Phe-C4-VC-PAB ...
T39307 Azido-PEG4-Val-Cit-PAB-MMAE Azido-PEG4-Val-Cit-PAB-MMAE
Azido-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugates (ADCs), comprising the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor), connected through the cleavable linker Az...
T17789 DBCO-(PEG2-VC-PAB-MMAE)2 Others
DBCO-(PEG2-VC-PAB-MMAE)2 consists of Monomethyl auristatin E (MMAE), a toxin payload in antibody-drug conjugate [1], conjugated to the cleavable linker DBCO-(PEG2-VC-PAB)2. MMAE, a potent tubulin inhibitor, serves as the...
T77838 Telisotuzumab vedotin ABBV-399
Telisotuzumab vedotin (ABBV-399), an antibody-drug conjugate (ADCs), targets c-Met and comprises the cytotoxic agent Monomethyl Auristatin E (MMAE), the Telisotuzumab antibody, and a cleavable mc-val-cit-PABC linker. Thi...
T77883 Val-Ala-PAB-MMAE
Val-Ala-PAB-MMAE is a drug-linker conjugate utilized in antibody-drug conjugates (ADCs), composed of the ADC linker Val-Ala-PAB and the cytotoxic agent monomethyl auristatin E (MMAE), which serves as a potent inhibitor o...
T77823 Polatuzumab vedotin
Polatuzumab vedotin, an antibody-drug conjugate, selectively targets CD79b with a humanized anti-CD79b IgG1 monoclonal antibody bound to monomethyl auristatin E (MMAE), a robust microtubule inhibitor. This compound shows...
T81361 PSMA-Val-Cit-PAB-MMAE
PSMA-Val-Cit-PAB-MMAE is a novel PSMA-targeted small-molecule conjugate leveraging monomethyl auristatin E (MMAE) for prostate cancer chemotherapy.
T77881 Tisotumab vedotin
Tisotumab vedotin is an antibody-drug conjugate (ADC) that specifically targets tissue factor (TF). This compound combines a fully human monoclonal antibody directed against TF (TF-011) with the cytotoxic agent Monomethy...
T82384 Fmoc-Gly3-VC-PAB-MMAE
Fmoc-Gly3-VC-PAB-MMAE is a drug-linker conjugate utilized in antibody-drug conjugates (ADCs), composed of the potent cytotoxic agent Monomethyl auristatin E (MMAE) tethered via a cleavable linker [1].
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